From Black Box to Glass Box

Stop hallucinating science.
Start validating it.

Rete is the first agentic analyst that generates audit-ready evidence. We translate biological intent into executable code—running securely across your entire R&D pipeline.

Request Early Access How it works

/cluster/rete_session_04

● SECURE CONNECTION

User: This patient is non-responsive to Anti-PD1. Integrate H&E histology with the spatial transcriptomics to find a secondary target.

Rete Agent: I will segment the tumor islands from the H&E image, overlay the RNA expression data, and identify ligand-receptor pairs active at the necrotic boundary.

1. Multimodal Fusion (Image + RNA)...
2. Run Permutation Test (Ligand-Receptor)...
3. Filter for Significant PVR-TIGIT Interaction...

                        # 1. Multimodal Fusion (Image + RNA)
                        import squidpy as sq
                        sq.im.segment(img, layer="image", method="watershed")
                        sq.im.calculate_image_features(adata, img, features="texture")
                        

                        # 2. Run Permutation Test (Ligand-Receptor)
                        res = sq.gr.ligrec(
                            adata,
                            n_perms=1000,
                            cluster_key="spatial_leiden"
                        )
                        

                        # 3. Filter for Significant PVR-TIGIT Interaction
                        pval = res['pvalues'].loc['Tumor', 'Stroma']['PVR_TIGIT']
                        print(f"P-Value: {pval:.5f}")
                        >> P-Value: 0.00132 (Significant)
                    

The Risk

A "probably right" answer is a regulatory liability.

Current AI tools act like search engines—they give you an answer based on hidden embeddings. In drug discovery, this is a dead end.

You cannot put a neural network's intuition into an IND filing or a clinical protocol. You need biological mechanism and auditable logic.

The Rete Difference

We don't replace the scientist. We arm them.

Instead of giving you a black-box label, Rete generates the executable code that proves why a result is valid.

We convert "AI Hallucination" into
Reproducible Science.

Flexible Deployment

We bring the brain to your data.

Whether you are a lean startup or a regulated enterprise, Rete deploys where you need it.

Fastest Start

Managed SaaS

Instant access to our secure, SOC 2 compliant cloud. Ideal for Biotech startups and non-IP datasets.

Private Cloud

We deploy Rete's containerized agents directly into your AWS/GCP/Azure VPC. Data never egresses.

Max Security

Air-Gapped

Run fully offline on your internal Kubernetes cluster. Zero external connectivity for critical IP.

A computational engine for the whole pipeline.

Rete is programmable for any modality. Here are three examples
of workflows our partners are automating today:

// EXAMPLE_01: MULTIMODAL FUSION

Spatial Target ID

Fuse H&E pathology images with gene expression layers. Deconvolute the tumor microenvironment using both morphology and molecular data.

// EXAMPLE_02: SYSTEMS BIO

Mechanism of Action

Validate how drugs perturb biological networks. Verify on-target vs. off-target effects with statistical rigor.

// EXAMPLE_03: CLINICAL

Biomarker Stratification

Analyze clinical cohorts to identify responder populations. Turn complex patient data into inclusion criteria.

Stop hallucinating science. Start validating it.